Vitamin A and D Deficiencies Associated With Incident Tuberculosis in HIV-Infected Patients Initiating Antiretroviral Therapy in Multinational Case-Cohort Study
JAIDS Journal of Acquired Immune Deficiency Syndromes2017Vol. 75(3), pp. e71–e79
Citations Over TimeTop 10% of 2017 papers
Mark W. Tenforde, Ashish Yadav, David W. Dowdy, Nikhil Gupte, Rupak Shivakoti, Wei-Teng Yang, Noluthando Mwelase, Cecilia Kanyama, Sandy Pillay, Wadzanai Samaneka, Breno Santos, Selvamuthu Poongulali, Srikanth Tripathy, Cynthia Riviere, Sima Berendes, Javier R. Lama, Sandra Wagner Cardoso, Patcharaphan Sugandhavesa, Parul Christian, Richard D. Semba, Thomas Campbell, Amita Gupta, the NWCS319 and ACTG 5175 study team
Abstract
In a diverse cohort of HIV-infected adults from predominantly low- and middle-income countries, deficiencies in vitamin A and vitamin D at ART initiation were independently associated with increased risk of incident TB in the ensuing 96 weeks. Vitamin A and D may be important modifiable risk factors for TB in high-risk HIV-infected patients starting ART in resource-limited highly-TB-endemic settings.
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