Chai-1: Decoding the molecular interactions of life
bioRxiv (Cold Spring Harbor Laboratory)2024
Citations Over Time
Chai Discovery, Jacques Boitreaud, Jack Dent, Matt McPartlon, Joshua Meier, Vinicius Torres dos Reis, Alex Rogozhnikov, Kevin Wu
Abstract
Abstract We introduce Chai-1, a multi-modal foundation model for molecular structure prediction that performs at the state-of-the-art across a variety of tasks relevant to drug discovery. Chai-1 can optionally be prompted with experimental restraints (e.g. derived from wet-lab data) which boosts performance by double-digit percentage points. Chai-1 can also be run in single-sequence mode with-out MSAs while preserving most of its performance. We release Chai-1 model weights and inference code as a Python package for non-commercial use and via a web interface where it can be used for free including for commercial drug discovery purposes.
Related Papers
- A Review of Researches on XUE Bao-chai between 2000-2010(2012)
- A Matter of Right and Wrong on the Theory of “Unite Chai and Dai as One"(2005)
- Susquehanna Chorale Spring Concert "Roots and Wings"(2017)
- → ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ(2024)
- City of chai : chai shop in Calcutta(1999)