An Evaluation Framework for Lossy Compression of Genome Sequencing Quality Values
2016Vol. 331, pp. 221–230
Citations Over TimeTop 10% of 2016 papers
Claudio Alberti, Noah M. Daniels, Mikel Hernáez, Jan Voges, Rachel L. Goldfeder, Ana A. Hernandez-Lopez, Marco Mattavelli, Bonnie Berger
Abstract
This paper provides the specification and an initial validation of an evaluation framework for the comparison of lossy compressors of genome sequencing quality values. The goal is to define reference data, test sets, tools and metrics that shall be used to evaluate the impact of lossy compression of quality values on human genome variant calling. The functionality of the framework is validated referring to two state-of-the-art genomic compressors. This work has been spurred by the current activity within the ISO/IEC SC29/WG11 technical committee (a.k.a. MPEG), which is investigating the possibility of starting a standardization activity for genomic information representation.
Related Papers
- LOSSLESS DATA COMPRESSION TECHNIQUES AND COMPARISON BETWEEN THE ALGORITHMS(2015)
- → Data Reduction Using Lossy Compression for Cosmology and Astrophysics Workflows(2019)1 cited
- Analysis of common lossless compression algorithm(2009)
- → Compression of Remotely Sensed Images using Self Organizing Feature Maps(1992)4 cited
- TECHNOLOGY DATA COMPRESSION TECHNIQUE USING HUFFMAN CODE FOR WIRELESS SENSOR NETWORK(2015)