Genome‐wide association meta‐analysis of age at first cannabis use
Addiction2018Vol. 113(11), pp. 2073–2086
Citations Over TimeTop 10% of 2018 papers
Camelia C. Minică, Karin J. H. Verweij, Peter J. van der Most, Hamdi Mbarek, Manon Bernard, Kristel R. van Eijk, Penelope A. Lind, Meng Zhen Liu, Dominique Maciejewski, Teemu Palviainen, Cristina Sánchez‐Mora, Richard Sherva, Michelle Taylor, Raymond K. Walters, Abdel Abdellaoui, T. Bernard Bigdeli, Susan Branje, Sandra A. Brown, Miguel Casas, Robin P. Corley, George Davey Smith, Gareth E. Davies, Erik A. Ehli, Lindsay A. Farrer, Iryna O. Fedko, Iris Garcia‐Martínez, Scott D. Gordon, Catharina A. Hartman, Andrew C. Heath, Ian B. Hickie, Matthew Hickman, Christian J. Hopfer, Jouke‐Jan Hottenga, René S. Kahn, Jaakko Kaprio, Tellervo Korhonen, Henry R. Kranzler, Ken Krauter, P.A.C. van Lier, Pamela A. F. Madden, Sarah E. Medland, Michael C. Neale, Wim Meeus, Grant W. Montgomery, Ilja M. Nolte, Albertine J. Oldehinkel, Zdenka Pausová, Josep Antoni Ramos‐Quiroga, Vanesa Richarte, Richard J. Rose, Jean Shin, Michael C. Stallings, Tamara L. Wall, Jennifer J. Ware, Margaret J. Wright, Hongyu Zhao, Hans M. Koot, Tomáš Paus, John K. Hewitt, Marta Ribasès, Anu Loukola, Marco P. Boks, Harold Snieder, Marcus R. Munafò, Joel Gelernter, Dorret I. Boomsma, Nicholas G. Martin, Nathan A. Gillespie, Jacqueline M. Vink, Eske M. Derks
Abstract
Age at cannabis initiation appears to be moderately heritable in western countries, and individual differences in onset can be explained by separate but correlated genetic liabilities. The significant association between age of initiation and ATP2C2 is consistent with the role of calcium signalling mechanisms in substance use disorders.
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