Genetic liability for prescription opioid use and risk of cardiovascular diseases: a multivariable Mendelian randomization study
Addiction2021Vol. 117(5), pp. 1382–1391
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Jiahao Cai, Lei He, Hongxuan Wang, Xiaoming Rong, Ming Chen, Qingyu Shen, Xiangpen Li, Mei Li, Ying Peng
Abstract
Mendelian randomization estimates provide robust evidence for the causal effects of genetic liability for prescription opioid use on an increased risk of coronary heart disease and myocardial infarction, which might be mediated by obesity-related traits.
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