Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma
Allergy2016Vol. 72(1), pp. 126–136
Citations Over TimeTop 17% of 2016 papers
Latifa Chachi, Mahnaz Abbasian, Adelina Gavrila, Abdulrahman Alzahrani, Omar Tliba, Peter Bradding, Andrew J. Wardlaw, Christopher E. Brightling, Yassine Amrani
Abstract
PP5-dependent impairment of GRα function represents a novel mechanism driving GC insensitivity in ASM in severe asthma.
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