Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients
Allergy2016Vol. 72(3), pp. 473–482
Citations Over TimeTop 24% of 2016 papers
Michael A. Portelli, Christopher Moseley, Claire E. Stewart, Dirkje S. Postma, Peter Howarth, J WARNER, John W. Holloway, Gerard H. Koppelman, Christopher E. Brightling, Ian Sayers
Abstract
This study provides novel data that elevated airway and blood uPAR is a feature of asthma and that blood uPAR is particularly related to severe, nonatopic asthma. The findings warrant further investigation and may provide a therapeutic opportunity for this refractory population.
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