Recent developments and highlights in mechanisms of allergic diseases: Microbiome
Allergy2018Vol. 73(12), pp. 2314–2327
Citations Over TimeTop 1% of 2018 papers
Nonhlanhla Lunjani, Pattraporn Satitsuksanoa, Zuzanna Łukasik, Milena Sokołowska, Thomas Eiwegger, Liam O’Mahony
Abstract
All body surfaces are exposed to a wide variety of microbes, which significantly influence immune reactivity within the host. This review provides an update on some of the critical novel findings that have been published on the influence of the microbiome on atopic dermatitis, food allergy and asthma. Microbial dysbiosis has consistently been observed in the skin, gut and lungs of patients with atopic dermatitis, food allergy and asthma, respectively, and the role of specific microbes in allergic disorders is being intensively investigated. However, many of these discoveries have yet to be translated into routine clinical practice.
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