Identification of novel biomarkers to distinguish bradykinin‐mediated angioedema from mast cell‐/histamine‐mediated angioedema
Allergy2021Vol. 77(3), pp. 946–955
Citations Over TimeTop 12% of 2021 papers
Abstract
This study is the first to compare HAE, ACE-AE, and CSU-AE. Although significance is limited by small sample size, Tie-2 was identified as a new promising biomarker candidate for HAE. FAP- α and tPA might serve as a marker for AE in general, whereas sE-selectin and Ang-2 were increased in BK-AE only. Our results add information to the role of endothelial dysfunction and serine proteases in different AE subtypes.
Related Papers
- → Bradykinin and the pathophysiology of angioedema(2003)214 cited
- → Preliminary results of a non-interventional single-center study evaluating the efficacy of long-term use of lanadelumab in routine clinical practice in the Russian Federation(2023)2 cited
- → Mechanism of Bradykinin-Induced Histamine Release from Rat Peritoneal Mast Cells.(1996)5 cited
- → (1981)
- → Review of: "Picomolar Sensitivity Analysis of Multiple Bradykinin-Related Peptides in the Blood Plasma of Patients With Hereditary Angioedema in Remission: A Pilot Study"(2022)