Small non‐coding RNA sequencing reveals global dysregulation of piwi‐interacting RNA (piRNA) expression in gonadal malignant germ cell tumours
Andrology2022Vol. 11(4), pp. 738–755
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Sean Laidlaw, Luz Alonso‐Crisostomo, Shivani Bailey, Harpreet K. Saini, Attila Molnár, James C. Nicholson, Anton J. Enright, Cinzia G. Scarpini, Raheleh Rahbari, Nicholas Coleman, Matthew J. Murray, on behalf the Children's Cancer and Leukaemia Group
Abstract
This study confirms previous miRNA observations, giving credence to our novel demonstration of global piRNA dysregulation in gonadal malignant GCTs, through both ME and non-ME-associated pathways, which likely contributes to GCT pathogenesis.
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