The inter‐relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis
Alimentary Pharmacology & Therapeutics2016Vol. 44(10), pp. 1039–1050
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Jessica Dyson, Nina Wilkinson, Laura Jopson, George Mells, Andrew Bathgate, M. Heneghan, James Neuberger, Gideon M. Hirschfield, SJ Ducker, Richard Sandford, Graeme Alexander, Deborah Stocken, Diana Jones
Abstract
The majority of patients with primary biliary cholangitis do not feel their QoL is impaired, although impairment is reported by a sizeable minority. Age at presentation is associated with impact on perceived QoL and the symptoms impairing it, with younger patients being more affected. Social dysfunction makes the greatest contribution to QoL impairment, and it should be targeted in trials aimed at improving life quality.
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