Endoscopic and clinical responses to anti‐tubercular therapy can differentiate intestinal tuberculosis from Crohn's disease
Alimentary Pharmacology & Therapeutics2016Vol. 45(1), pp. 27–36
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V. Pratap Mouli, Khushboo Munot, Ashwin N. Ananthakrishnan, Saurabh Kedia, Sree Siva Kumar Raja Addagalla, Sushil Kumar Garg, Jaya Benjamin, Vikas Singla, Renu Dhingra, Veena Tiwari, Sawan Bopanna, Susan Hutfless, Govind Makharia, Vineet Ahuja
Abstract
Disproportionately lower mucosal healing rate despite an overall symptom response with 6 months of anti-tubercular therapy in patients with Crohn's disease suggests a need for repeat colonoscopy for diagnosing Crohn's disease. Patients with intestinal tuberculosis showing significant symptomatic response after 2-3 months of anti-tubercular therapy, suggest that symptom persistence after a therapeutic trial of 3 months of anti-tubercular therapy may indicate the diagnosis of Crohn's disease.
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