Senescence mirrors the extent of liver fibrosis in chronic hepatitis C virus infection
Alimentary Pharmacology & Therapeutics2018Vol. 48(3), pp. 270–280
Citations Over TimeTop 15% of 2018 papers
Franziska Wandrer, Byungjoo Han, Stephanie Liebig, Jérôme Schlué, Michael P. Manns, Klaus Schulze‐Osthoff, Heike Bantel
Abstract
Senescence of hepatic T-cells is enhanced in chronic viral hepatitis and increases with fibrosis progression. Serological detection of senescence-associated chitotriosidase might allow for the non-invasive detection of relevant fibrosis stages.
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