Clinical classification and long‐term outcomes of seronegative coeliac disease: a 20‐year multicentre follow‐up study
Alimentary Pharmacology & Therapeutics2021Vol. 54(10), pp. 1278–1289
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Annalisa Schiepatti, Anupam Rej, Stiliano Maimaris, Simon S. Cross, Petra Porta, Imran Aziz, Timothy J. Key, John Goodwin, Amélie Therrien, Shakira Yoosuf, Daniel A. Leffler, Jocelyn A. Silvester, Catherine Klersy, Federico Biagi, David S. Sanders
Abstract
Seronegative coeliac disease has a more aggressive disease phenotype than seropositive coeliac disease. These data argue against over-reliance on serology for the diagnosis of coeliac disease and support a strict clinical and histologic follow-up in seronegative coeliac disease.
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