Physiologically‐based pharmacokinetic modeling of renally excreted antiretroviral drugs in pregnant women
British Journal of Clinical Pharmacology2015Vol. 80(5), pp. 1031–1041
Citations Over TimeTop 10% of 2015 papers
Maïlys De Sousa Mendes, Déborah Hirt, Saı̈k Urien, Elodie Valade, Naïm Bouazza, Frantz Foissac, Stéphane Blanche, Jean‐Marc Tréluyer, Sihem Benaboud
Abstract
Pregnancy PBPK models are useful tools to quantify a priori the drug exposure changes during pregnancy for renally excreted drugs. These models can be applied to evaluate alternative dosing regimens to optimize drug therapy during pregnancy.
Related Papers
- → Physiologically Based Pharmacokinetic Modelling to Predict Pharmacokinetics of Enavogliflozin, a Sodium-Dependent Glucose Transporter 2 Inhibitor, in Humans(2023)10 cited
- → A physiologically-based pharmacokinetic model adequately predicted the human pharmacokinetic profiles of YH4808, a novel K+-competitive acid blocker(2019)7 cited
- → Physiologically Based Pharmacokinetic Modelling and Prediction of Metformin Pharmacokinetics in Renal/Hepatic-Impaired Young Adults and Elderly Populations(2017)24 cited
- [Predicting pharmacokinetics of anti-cancer drug, famitinib in human using physiologically based pharmacokinetic model].(2014)
- → Physiologically Based Models: Techniques and Applications to Drug Delivery(2021)