Prediction of human fetal pharmacokinetics usingex vivohuman placenta perfusion studies and physiologically based models
British Journal of Clinical Pharmacology2015Vol. 81(4), pp. 646–657
Citations Over TimeTop 10% of 2015 papers
Maïlys De Sousa Mendes, Déborah Hirt, Cécile Vinot, Elodie Valade, Gabrielle Lui, Claire Pressiat, Naïm Bouazza, Frantz Foissac, Stéphane Blanche, Minh Lê, Gilles Peytavin, Jean‐Marc Tréluyer, Saı̈k Urien, Sihem Benaboud
Abstract
The integration of ex vivo human placental perfusion parameters in a p-PBPK model should be a promising new approach for predicting human fetal exposure to xenobiotics.
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