In vitrotest to confirm diagnosis of allopurinol-induced severe cutaneous adverse reactions
British Journal of Dermatology2016Vol. 175(5), pp. 994–1002
Citations Over TimeTop 10% of 2016 papers
Jettanong Klaewsongkram, Pattarawat Thantiworasit, Nithikan Suthumchai, Pawinee Rerknimitr, Chonlaphat Sukasem, Papapit Tuchinda, Leena Chularojanamontri, Yuttana Srinoulprasert, Ticha Rerkpattanapipat, Kumutnart Chanprapaph, Wareeporn Disphanurat, Panlop Chakkavittumrong, Napatra Tovanabutra, Chutika Srisuttiyakorn
Abstract
The measurement of oxypurinol/anti-PD-L1-inducing IFN-γ-releasing cells yields a high diagnostic value in distinguishing between allopurinol-allergic and control subjects. This technique is beneficial in confirming diagnosis of allopurinol-induced SCARs in patients whose reaction develops while taking multiple drugs.
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