Do perioperative antibiotics reduce the risk of surgical-site infections following excision of ulcerated skin cancers? A Critically Appraised Topic
British Journal of Dermatology2017Vol. 178(2), pp. 394–399
Citations Over TimeTop 22% of 2017 papers
S. Chan, Aaron Wernham, Natasha Stembridge, Natasha Harper, S. Verykiou, Georgina Fremlin, Rachel Abbott, Rubeta Matin
Abstract
The heterogeneity of the RCTs included in this study makes it difficult to make a direct comparison of the outcomes measured. High-quality evidence demonstrating a beneficial effect of the use of perioperative antibiotics to prevent SSI following excision of ulcerated skin cancers is lacking. In the absence of an evidence base, we propose that a well-designed multicentre RCT could evaluate the effect of perioperative antibiotics following excision of ulcerated tumours, and potentially reduce inappropriate antibiotic prescription.
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