Eccrine sweat glands associate with the human hair follicle within a defined compartment of dermal white adipose tissue
British Journal of Dermatology2018Vol. 178(5), pp. 1163–1172
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Enrique Poblet, Francisco Jiménez, E. Escario-Travesedo, J. Hardman, Irene Hernández, José Luis Agudo-Mena, Juan J. Cabrera, Carina Nicu, Ralf Paus
Abstract
We propose a model of functional human skin anatomy in which ESGs are closely associated with the PSU and the dWAT to form a common homeostatic tissue environment, which may best be encapsulated in the term 'adnexal skin unit'. The challenge now is to dissect how each component of this superstructure of human skin functionally cooperates with and influences the other under physiological conditions, during regeneration and repair and in selected skin diseases.
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