Measurement of cytokines and chemokines and association with clinical severity of dermatomyositis and clinically amyopathic dermatomyositis
British Journal of Dermatology2018Vol. 179(6), pp. 1334–1341
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M. Chen, Cheng Quan, Lingfeng Diao, Feng Xue, Ke Xue, Bo Wang, X. Li, Xiaomei Zhu, Jie Zheng, Hua Cao
Abstract
Serum levels of IFN-β and CXCL10 may be useful biomarkers for assessing cutaneous disease activity in patients with DM and CADM. In addition, serum IL-6, IL-10, IL-18 and IFN-β were highly correlated with the occurrence of A/SIP. These cytokines may play a role in the pathogenesis of DM and CADM.
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