Pharmacology of AMG 181, a human anti‐α4β7 antibody that specifically alters trafficking of gut‐homing T cells
British Journal of Pharmacology2013Vol. 169(1), pp. 51–68
Citations Over TimeTop 10% of 2013 papers
WJ Pan, H. Hsu, WA Rees, SP Lear, F Lee, IN Foltz, Palaniswami Rathanaswami, Kathy Manchulenko, Chan Bm, M Zhang, XZ Xia, SK Patel, PJ Prince, DR Doherty, CM Sheckler, KO Reynhardt, C D Krill, BJ Harder, JA Wisler, JL Brandvig, JL Lynch, AA Anderson, LC Wienkers, Borie Dc
Abstract
AMG 181 has in vitro pharmacology, and pharmacokinetic/pharmacodynamic and safety characteristics in cynomolgus monkeys that are suitable for further investigation in humans.
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