Nitric oxide generation by the organic nitrate NDBP attenuates oxidative stress and angiotensin II‐mediated hypertension
British Journal of Pharmacology2016Vol. 173(14), pp. 2290–2302
Citations Over TimeTop 16% of 2016 papers
Suênia Karla Pacheco Porpino, Christa Zollbrecht, Maria Peleli, Marcelo F. Montenegro, Maria Cláudia Rodrigues Brandão, Petrônio Filgueiras de Athayde-Filho, Maria S. França-Silva, Erik Larsson, Jon O. Lundberg, Eddie Weitzberg, Erik Persson, Valdir A. Braga, Mattias Carlström
Abstract
The novel organic nitrate NDBP halts the progression of angiotensin II-mediated hypertension. Mechanistically, our findings suggest that NDBP treatment is associated with sustained NO release and attenuated activity of NADPH oxidase, which to some extent requires functional xanthine oxidase.
Related Papers
- → A novel fluorescent probe for the detection of nitric oxide in vitro and in vivo(2008)70 cited
- Nitric oxide :principles and actions(1996)
- → Multifunctional role of nitric oxide in inflammation(1994)108 cited
- → Selective Fluorescent Activation for Bioimaging the Expression of Nitric Oxide in Cellular and In Vivo Systems(2010)1 cited
- → DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION(2018)