The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain
British Journal of Pharmacology2016Vol. 173(16), pp. 2506–2520
Citations Over TimeTop 10% of 2016 papers
Deniz Bağdaş, Jenny L. Wilkerson, Abhijit Kulkarni, Wisam Toma, Shakir D. AlSharari, Zülfiye Gül, Aron H. Lichtman, Roger L. Papke, Ganesh A. Thakur, M. Imad Damaj
Abstract
Collectively, these results provide the first proof of principle that α7 ago-PAMs represent an effective pharmacological strategy for treating inflammatory and neuropathic pain.
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