Sex‐specific autistic endophenotypes induced by prenatal exposure to valproic acid involve anandamide signalling
British Journal of Pharmacology2018Vol. 175(18), pp. 3699–3712
Citations Over TimeTop 10% of 2018 papers
Francesca Melancia, Sara Schiavi, Michela Servadio, Veronica Cartocci, Patrizia Campolongo, Maura Palmery, Valentina Pallottini, Viviana Trezza
Abstract
These findings highlight sexually dimorphic consequences of prenatal VPA exposure that may be related to sex-specific effects of VPA on endocannabinoid neurotransmission in the course of development and introduce a new therapeutic target for reversing autistic-like symptoms in both sexes.
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