Small‐molecule inhibition of prostaglandin E receptor 2 impairs cyclooxygenase‐associated malignant glioma growth
British Journal of Pharmacology2019Vol. 176(11), pp. 1680–1699
Citations Over TimeTop 10% of 2019 papers
Jian-Ge Qiu, Qianqian Li, Katherine Bell, Xue Yao, Yifeng Du, Erik Zhang, Jane Yu, Ying Yu, Zhi Shi, Jianxiong Jiang
Abstract
Taken together, our results suggest that PGE2 signalling via the EP2 receptor increases the malignant potential of human glioma cells and might represent a novel therapeutic target for GBM.
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