Activation of thyroid hormone receptor‐β improved disease activity and metabolism independent of body weight in a mouse model of non‐alcoholic steatohepatitis and fibrosis
British Journal of Pharmacology2021Vol. 178(12), pp. 2412–2423
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Aimo Kannt, Paulus Wohlfart, Andreas Nygaard Madsen, Sanne Skovgård Veidal, Michael Feigh, Dieter Schmoll
Abstract
Our model robustly reflected clinical observations of body weight-independent improvements in systemic and hepatic metabolism including anti-steatotic activity.
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