Fluorescent‐ and tagged‐protoxin II peptides: potent markers of the Nav1.7 channel pain target
British Journal of Pharmacology2021Vol. 178(13), pp. 2632–2650
Citations Over Time
Jérôme Montnach, Stéphan De Waard, Sébastien Nicolas, Sophie Burel, Nancy Osorio, Claude Zoukimian, Massimo Mantegazza, Rachid Boukaiba, Rémy Béroud, Michel Partiseti, Patrick Delmas, Céline Marionneau, Michel De Waard
Abstract
The properties of these ProTx II analogues as tools for Nav channel purification and cell distribution studies pave the way for a better understanding of ProTx II channel receptors in pain and their pathophysiological implications in sensory neuronal processing. The new fluorescent ProTx II should also be useful in the design of new drug screening strategies.
Related Papers
- → Mechanism of Gating and Ion Conductivity of a Possible Tetrameric Pore in Aquaporin-1(2006)157 cited
- → Time-Resolved Measurement of State-Specific P2X2Ion Channel Cytosolic Gating Motions(2004)58 cited
- → Open- and closed-state fast inactivation in sodium channels(2010)30 cited
- → Pore-to-gate coupling of HCN channels revealed by a pore variant that contributes to gating but not permeation(2005)17 cited
- → Mechanosensitive channel MscL gating transitions coupling with constriction point shift(2024)2 cited