Established pulmonary hypertension in rats was reversed by a combination of a HIF‐2α antagonist and a p53 agonist
British Journal of Pharmacology2021Vol. 179(5), pp. 1065–1081
Citations Over TimeTop 10% of 2021 papers
Qiuyu Zheng, Wenju Lu, Yan Han, Xin Duan, Yuqin Chen, Chenting Zhang, Xiaoyun Luo, Jiyuan Chen, Chao Wang, Shiyun Liu, Yi Li, Haiyang Tang, Shamin Rahimi, Shayan Rahimi, Jason X.‐J. Yuan, Nanshan Zhong, Kai Yang, Jian Wang
Abstract
Combination treatment confers greater therapeutic efficacy against PH through a selective modulation of p53 and HIF-2α in PASMC and PAEC.
Related Papers
- → Intermittent short‐duration reoxygenation protects against simulated high altitude‐induced pulmonary hypertension in rats(2020)14 cited
- → Use of an antagonist for estimating the degree of agonist stimulation during physiological release(1995)10 cited
- → Reversal of hypoxia by treatment of pulmonary hypertension(2009)
- → Quantification of Protein Concentration using Single Molecule Western Blot(2012)
- Evaluation on the Cambridge Biotech HIV-1 Western blot kit(2006)