Ruthenium 360 and mitoxantrone inhibit mitochondrial calcium uniporter channel to prevent liver steatosis induced by high‐fat diet
British Journal of Pharmacology2021Vol. 179(11), pp. 2678–2696
Citations Over TimeTop 10% of 2021 papers
Zhiwang Zhang, Zupeng Luo, Lin Yu, Yang Xiao, Siqi Liu, Zhier Aluo, Zeqiang Ma, Liang Huang, Lianggui Xiao, Mengting Jia, Ziyi Song, Haojie Zhang, Yixing Li, Lei Zhou
Abstract
These findings provide molecular insights into the way HFD disrupts mitochondrial calcium homeostasis and identify MCU as a promising drug target for the treatment of hepatic steatosis.
Related Papers
- → A Biophysically Based Mathematical Model for the Kinetics of Mitochondrial Calcium Uniporter(2009)46 cited
- → Fluorescence spectroscopy to diagnose hepatic steatosis in a rat model of fatty liver(2009)19 cited
- → Rapid Decrease in Liver Graft Steatosis in the Early Post-transplant Period: A Blinded and Randomized Study(2019)3 cited
- → DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION(2018)
- → The mitochondrial calcium uniporter compensates for Complex I dysfunction(2021)