SANTAMARINE: Mechanistic studies on multiple diseases
Chemical Biology & Drug Design2020Vol. 95(4), pp. 427–434
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Abstract
Medicinal plants are vital sources of modern and traditional Chinese medicines. Sesquiterpene lactones (SLs) consist of a large group of plant secondary metabolites and belong to C15 terpenoid group. SLs have shown various biological activities including antitumor and anti-inflammatory activities. Santamarine (STM), C15 H20 O3 , is a kind of sesquiterpene lactone, whose molecular weight is 248.322 g/mol. Santamarine has been isolated from several plants species and has shown eminent biological activities, such as anticancer activity and anti-inflammatory activity. In this mini-review, we summarize the studies on the effects and the mechanisms of STM, and explore the avenues of application.
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