Clinical significance of small airway obstruction markers in patients with asthma
Clinical & Experimental Allergy2013Vol. 44(4), pp. 499–507
Citations Over TimeTop 12% of 2013 papers
Sherif Gonem, Sushiladevi Natarajan, Dhananjay Desai, Steven Corkill, Amisha Singapuri, Peter Bradding, Per Gustafsson, Rino Costanza, Radhika Kajekar, H. Parmar, Christopher E. Brightling, Salman Siddiqui
Abstract
Previously reported markers of small airway obstruction do not appear to be independently associated with asthma disease expression. In contrast, the IOS parameter R20, a marker of mean airway resistance of both large and small airways, appears to have independent clinical significance. These observations require confirmation in prospective longitudinal studies.
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