Local increase in IgE and class switch recombination to IgE in nasal polyps in chronic rhinosinusitis
Clinical & Experimental Allergy2014Vol. 44(5), pp. 701–712
Citations Over TimeTop 11% of 2014 papers
Shintaro Baba, Kenji Kondo, Makiko Toma‐Hirano, Kaori Kanaya, Kazumi Suzukawa, Munetaka Ushio, Maho Suzukawa, Ken Ohta, Tatsuya Yamasoba
Abstract
The current study suggests local class switching to IgE, production of IgE and IgE localization to the surface of mast cells in eosinophilic chronic rhinosinusitis in the Japanese population. The difference in the IgE-related profiles between eosinophilic chronic rhinosinusitis and non-eosinophilic chronic rhinosinusitis suggests heterogeneity in the pathogenesis of chronic rhinosinusitis with nasal polyps.
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