CD8+T cells with distinct cytokine‐producing features and low cytotoxic activity in eosinophilic and non‐eosinophilic chronic rhinosinusitis with nasal polyps
Clinical & Experimental Allergy2016Vol. 46(9), pp. 1162–1175
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Jingwei Ma, L.‐L. SHI, Yuwei Deng, Haozhou Wang, Peng Cao, Xiaobing Long, Xiaohui Zhang, Yan Liu, Ming Zeng, Z. Liu
Abstract
CD8(+) T cells have low cytotoxic activity; nevertheless, they are a significant and previously underappreciated source of inflammatory cytokine production in polyps. Different Tc cell subset domination may contribute to distinctly biased granulocyte inflammation in eosinophilic and non-eosinophilic polyps.
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