The relationship between biomarkers of fungal allergy and lung damage in asthma
Clinical & Experimental Allergy2016Vol. 47(1), pp. 48–56
Citations Over TimeTop 10% of 2016 papers
Kerry Woolnough, Matthew Richardson, Chris Newby, Matt Craner, Michelle Bourne, Will Monteiro, Salman Siddiqui, Peter Bradding, Catherine H. Pashley, Andrew J. Wardlaw
Abstract
IgE sensitisation to thermotolerant filamentous fungi, in particular A. fumigatus but not total IgE, is associated with fixed airflow obstruction and a number of radiological abnormalities in moderate to severe asthma. All patients with IgE sensitisation to A. fumigatus are at risk of lung damage irrespective of whether they meet the criteria for ABPA.
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