Effect of allergens and irritants on levels of natural moisturizing factor and corneocyte morphology
Contact Dermatitis2017Vol. 76(5), pp. 287–295
Citations Over TimeTop 10% of 2017 papers
Sjors A. Koppes, Suzana Ljubojević Hadžavdić, Ivone Jakaša, Nika Franceschi, Christoph Riethmüller, Ružica Jurakić Tončić, Branka Marinović, Nidhin Raj, Anthony V. Rawlings, R. Voegeli, Majella E. Lane, Marek Haftek, Monique H. W. Frings‐Dresen, Thomas Rustemeyer, Sanja Kežić
Abstract
MCI/MI significantly decreased NMF levels, similarly to SLS. The altered corneocyte morphology suggests that skin barrier damage plays a role in the pathogenesis of MCI/MI contact allergy. The DTI seems to differentiate reactions to SLS from those to the allergens tested, as SLS was the only agent that caused a DTI increase.
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