Childhood appendicitis and future risk of inflammatory bowel disease – A nationwide cohort study in Sweden 1973–2017
Colorectal Disease2022Vol. 24(8), pp. 975–983
Citations Over TimeTop 10% of 2022 papers
Abstract
Juvenile appendicitis treated with appendectomy was associated with a decreased risk of adult IBD, both UC and CD. Those treated conservatively instead of with surgery had a lower risk of UC only. Our findings warrant more research on the role of the appendix and gut microbiota in the pathogenesis of IBD.
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