TGF‐β1 peptide‐based inhibitor P144 ameliorates renal fibrosis after ischemia–reperfusion injury by modulating alternatively activated macrophages
Cell Proliferation2022Vol. 55(10), pp. e13299–e13299
Citations Over TimeTop 10% of 2022 papers
Delun Li, Jian Zhang, Siyu Yuan, Chao Wang, Jiakai Chang, Yan Tong, Ran Liu, Tian Sang, Lili Li, Jijun Li, Qing Ouyang, Xiangmei Chen
Abstract
Our study showed that the TGF-β1 peptide-based inhibitor P144 decreased renal fibrosis through the blockade of the TGF-β1-Smad3 signaling pathway and the modulation of macrophage polarization, suggesting its potential therapeutic use in IRI-induced renal fibrosis.
Related Papers
- Prevention of ischemia-reperfusion injury in rat ovarian tissue with the on-off method.(2011)
- → No safe renal warm ischemia time—The molecular network characteristics and pathological features of mild to severe ischemia reperfusion kidney injury(2022)19 cited
- → Prevention of renal damage by alpha tocopherol in ischemia and reperfusion models of rats(2003)27 cited
- Research of MCP-1 expression in rat's retina injured by ischemia-reperfusion(2003)
- [Brain and kidney renin-angiotensin system in rats with simultaneously induced cerebral and renal ischemia].(1980)