Does early intensive multifactorial therapy reduce modelled cardiovascular risk in individuals with screen‐detected diabetes? Results from the ADDITION‐Europe cluster randomized trial
Diabetic Medicine2014Vol. 31(6), pp. 647–656
Citations Over TimeTop 14% of 2014 papers
James A Black, Stephen J. Sharp, Nicholas J. Wareham, Annelli Sandbæk, Guy E.H.M. Rutten, T. Lauritzen, Kamlesh Khunti, Melanie J. Davies, K. Borch‐Johnsen, Simon J. Griffin, Rebecca K. Simmons
Abstract
Despite increasing age and diabetes duration, there was a decline in modelled cardiovascular disease risk in the 5 years following diagnosis. Compared with routine care, 10-year modelled cardiovascular disease risk was lower in the intensive treatment group at 5 years. Our results suggest that patients benefit from intensive treatment early in the diabetes disease trajectory, where the rate of cardiovascular disease risk progression may be slowed.
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