Acute physiological effects of glucocorticoids on fuel metabolism in humans are permissive but not direct
Diabetes Obesity and Metabolism2017Vol. 19(6), pp. 883–891
Citations Over TimeTop 10% of 2017 papers
Roland H. Stimson, Anna J. Anderson, Lynne Ramage, David P. Macfarlane, A. C. de Beaux, Damian J. Mole, Ruth Andrew, Brian R. Walker
Abstract
The acute lipolytic effects of cortisol require supraphysiological concentrations, are dependent on insulin and adrenaline and are observed only in subcutaneous adipose tissue. The resistance of visceral adipose tissue to cortisol's lipolytic effects may contribute to the central fat accumulation observed with chronic glucocorticoid excess.
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