Intrahepatic cholestasis in common chronic liver diseases
European Journal of Clinical Investigation2013Vol. 43(10), pp. 1069–1083
Citations Over TimeTop 15% of 2013 papers
Christoph Jüngst, Thomas Berg, Jun Cheng, Richard M. Green, Jidong Jia, Andrew L. Mason, Frank Lammert
Abstract
Dependent on the aetiology, intrahepatic cholestasis is present at variable frequencies and in different disease stages in chronic liver diseases. Cholestasis secondary to chronic liver injury may denote a severe disease course and development of end-stage liver disease or specific disease variants. These findings indicate that 'secondary intrahepatic cholestasis' (SIC) can occur in the natural course of chronic liver diseases other than the primary cholestatic diseases, in particular in the setting of advanced disease progression.
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