EFNS/ENS Consensus on the diagnosis and management of chronic ataxias in adulthood
European Journal of Neurology2014Vol. 21(4), pp. 552–562
Citations Over TimeTop 10% of 2014 papers
Bart P.C. van de Warrenburg, Judith van Gaalen, Sylvia Boesch, Jean‐Marc Burgunder, Alexandra Dürr, Paola Giunti, Thomas Klockgether, Caterina Mariotti, Massimo Pandolfo, O. Riess
Abstract
Some of the rare recessive ataxias are treatable, but for most of the heredodegenerative ataxias treatment is purely symptomatic. Idebenone is not effective in Friedreich's ataxia (level A). Riluzole (level B) and amantadine (level C) might provide symptomatic relief, irrespective of exact etiology. Also, varenicline for SCA3 patients (level B) can be considered. There is level Class II evidence to recommend physiotherapy, and Class III data to support occupational therapy.
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