Increased endothelial activation in recently symptomatic versus asymptomatic carotid artery stenosis and in cerebral microembolic‐signal‐negative patient subgroups
European Journal of Neurology2014Vol. 21(7), pp. 969–969
Citations Over TimeTop 19% of 2014 papers
J. A. Kinsella, W. Oliver Tobin, G. F. Kavanagh, James S. O’Donnell, Rachel T. McGrath, Sean Tierney, T.M. Feeley, Bridget Egan, Desmond O’Neill, Rónán Collins, Tara Coughlan, Joseph Harbison, Colin P. Doherty, Prakash Madhavan, D. J. Moore, Siobhan O’Neill, Mary Paula Colgan, Maher Saqqur, Raymond P. Murphy, Niamh Moran, George Hamilton, Dominick J. H. McCabe
Abstract
Endothelial activation is enhanced in symptomatic versus asymptomatic carotid stenosis patients, in early symptomatic versus asymptomatic MES-negative patients, and decreases over time in symptomatic patients. VWF:Ag II levels are a more sensitive marker of endothelial activation than VWF:Ag levels in carotid stenosis. The potential value of endothelial biomarkers and concurrent cerebral MES detection at predicting stroke risk in carotid stenosis warrants further study.
Related Papers
- → Low Risk of Ipsilateral Stroke in Patients With Asymptomatic Carotid Stenosis on Best Medical Treatment(2009)455 cited
- → Absence of Microemboli on Transcranial Doppler Identifies Low-Risk Patients With Asymptomatic Carotid Stenosis(2005)244 cited
- → Ambulatory Transcranial Doppler Cerebral Embolic Signal Detection in Symptomatic and Asymptomatic Carotid Stenosis(2005)52 cited
- → Synchronous Cardiac and Carotid Revascularisation: The Devil is in the Detail(2010)21 cited
- → Asymptomatic Carotid Bruit and Stenosis(1986)50 cited