Responsiveness of clinical outcome measures in Charcot−Marie−Tooth disease
European Journal of Neurology2015Vol. 22(12), pp. 1556–1563
Citations Over TimeTop 11% of 2015 papers
Giuseppe Piscosquito, Mary M. Reilly, Angelo Schenone, G Fabrizi, Tiziana Cavallaro, Lucio Santoro, Fiore Manganelli, Giuseppe Vita, Aldo Quattrone, Luca Padua, Franco Gemignani, Francesco Visioli, Matilde Laurá, Daniela Calabrese, Richard AC Hughes, D. Radice, Alessandra Solari, Davide Pareyson, the CMT‐TRIAAL and CMT‐TRAUK Group
Abstract
Overall these OMs showed low or negligible responsiveness, confirming the need to improve current OMs and to develop novel ones for prognostic and interventional studies. However, handgrip and foot dorsiflexion myometry are worth retaining for future trials as they were the most responsive and are likely to be clinically relevant for patients.
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