Gut microbiota in early pediatric multiple sclerosis: a case−control study
European Journal of Neurology2016Vol. 23(8), pp. 1308–1321
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Helen Tremlett, Douglas Fadrosh, Ali A. Faruqi, Feng Zhu, Jason Hart, Shelly Roalstad, Jennifer Graves, Shalini Lynch, Emmanuelle Waubant
Abstract
In recent onset pediatric MS, perturbations in the gut microbiome composition were observed, in parallel with predicted enrichment of metabolic pathways associated with neurodegeneration. Findings were suggestive of a pro-inflammatory milieu.
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