More than constipation – bowel symptoms in Parkinson's disease and their connection to gut microbiota
European Journal of Neurology2017Vol. 24(11), pp. 1375–1383
Citations Over TimeTop 10% of 2017 papers
Tuomas Mertsalmi, Velma T. E. Aho, Pedro A. B. Pereira, Lars Paulín, Eero Pekkonen, Petri Auvinen, Filip Scheperjans
Abstract
Our results indicate that PD patients may suffer from colonic dysfunction beyond pure constipation. Therefore, a more comprehensive assessment of bowel symptoms could provide valuable information. The lower abundance of Prevotella bacteria in PD patients with IBS-like symptoms suggests that the microbiota-gut-brain axis may be implicated in the gastrointestinal dysfunction of PD patients.
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