Brain functional connectome abnormalities in amyotrophic lateral sclerosis are associated with disability and cortical hyperexcitability
European Journal of Neurology2017Vol. 24(12), pp. 1507–1517
Citations Over TimeTop 10% of 2017 papers
Nimeshan Geevasinga, Mayuresh S. Korgaonkar, Parvathi Menon, Mehdi van den Bos, L. Gomes, Sheryl Foster, Matthew C. Kiernan, Steve Vucic
Abstract
Multimodal assessment of cortical function in patients with ALS identified deficits in functional connectivity associated with cortical hyperexcitability that correlated with patient disability. Novel integration of functional brain assessment further contributes to the understanding of disease pathogenesis in ALS.
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