Early plasma biomarker dynamic profiles are associated with acute ischemic stroke outcomes
European Journal of Neurology2022Vol. 29(6), pp. 1630–1642
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Manuel Correia, Isabel Silva, Denis Gabriel, Joel Simrén, Ângelo Carneiro, Sara Ribeiro, Hugo Mota Dória, Ricardo Varela, Ana Aires, Karolina Minta, Rui Antunes, Rui Felgueiras, Pedro Castro, Kaj Blenow, Rui Magalhães, Henrik Zetterberg, Luı́s F. Maia
Abstract
Early GFAP, t-tau and NfL rate-of-change in plasma can predict AIS clinical and neuroimaging outcome after successful recanalization. Such dynamic measures match and anticipate neuroimaging predictive capacity, potentially improving AIS patient stratification for treatment, and targeting individualized stroke care.
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