Patterns of neurotoxicity among patients receiving chimeric antigen receptor T‐cell therapy: A single‐centre cohort study
European Journal of Neurology2023Vol. 31(3), pp. e16174–e16174
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Carmela Sales, Mary Ann Anderson, Valeriya Kuznetsova, Hannah Rosenfeld, Charles B. Malpas, Izanne Roos, Michael Dickinson, Simon J. Harrison, Tomáš Kalinčík
Abstract
The patterns of CAR-T-related neurotoxicity often include change in handwriting, tremor, and mild confusional state, especially early in their evolution. These may remain undetected by routine neurological surveillance. These features represent accessible clinical markers of incipient ICANS.
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