Mapping electrophysiological connectivity of pulvinar in seizure propagation and neuromodulation
Epilepsia2025Vol. 66(11), pp. 4308–4323
Citations Over TimeTop 10% of 2025 papers
Yuan Yao, Xiu Wang, Baotian Zhao, Wenhan Hu, Liang Wang, Xiaoqiu Shao, Zhihao Guo, Bowen Yang, Zilin Li, Du Cai, Xiuliang Fan, Josef Parvizi, Kai Zhang, Chao Zhang
Abstract
Our study supports emerging evidence for pulvinar involvement in seizure propagation. The data with RSEPS also map PuM causal connectivity in the human brain. Although the clinical utility of pulvinar neuromodulation in patients with DRE remains to be determined by prospective clinical trials, our findings provide a convincing link between PuM neuromodulation and the reduction of epileptic activity.
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