Histamine in Migraine and Brain
Headache The Journal of Head and Face Pain2014Vol. 54(2), pp. 246–259
Citations Over TimeTop 10% of 2014 papers
Abstract
The role of the central histaminergic system in migraine is largely unexplored, but findings from preclinical research may be linked to several aspects of the disorder. The histaminergic system of the brain may play an important role, especially in the initial phase of an attack, and histamine H3 and H4 receptor ligands may potentially have migraine prophylactic properties. However, the basis for this is still circumstantial, and the evidence is lacking.
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